منابع مشابه
Epigenetic biomarker development.
Epigenetic mechanisms control gene expression in a way that is stably propagated over multiple cell divisions, but which is also flexible enough to respond to environmental influences. This intermediate position between stability and plasticity renders epigenetic information highly useful for monitoring cellular states in the context of personalized medicine. Epigenetic alterations have also be...
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Biomarkers are molecules or features which can provide clinically-relevant information about a particular disease state, thus providing useful tools for oncologists. Recently, a number of studies have demonstrated that DNA methylation holds great promise as a novel source of cancer biomarkers. Although promoter regions have been the focus of most investigations thus far, mounting evidence demon...
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Background: Resistin and ghrelin are hormones that have roles in the glucose and lipid homeostasis and weight regulation. Human studies regarding resistin and ghrelin in diabetic patients are scarce, especially in the cases of normotensive and non-obese patients. This study was designed to illuminate some of the missing points.Methods: Eighty diabetic patients and eighty healthy individuals par...
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Research into the cell biology of intracellular pathogens has provided information on host-pathogen interactions and on the importance of lipids at various stages in the interactions. Lipids are “gatekeepers” in important chemical reactions involving cell signaling during pathogen docking, invasion and traffic in and out of cells. Working with the Novartis Institute for Tropical Diseases, our t...
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ژورنال
عنوان ژورنال: Epigenomics
سال: 2009
ISSN: 1750-1911,1750-192X
DOI: 10.2217/epi.09.6